Histry Chem

Знание

Material Safety Data Sheet: Propylene Glycol BIO

Identification

Product Name: Propylene Glycol BIO
Chemical Family: Glycol
Synonyms: 1,2-Propanediol, PG
CAS Number: 57-55-6
Manufactured by: Leading chemical suppliers committed to sustainable production
Recommended Use: Ingredient in pharmaceuticals, food, cosmetics, and industrial products
Contact for Information: Safety and technical services department from responsible supplier or producer
Emergency Phone: Refer to local emergency numbers or internal emergency response services
Address: Physical location of the responsible party providing this information

Hazard Identification

Classification: Not classified as hazardous under GHS standards
Signal Word: None
Hazard Statements: Non-toxic at typical concentrations, may cause mild irritation
Precautionary Statements: Avoid direct inhalation, limit unnecessary skin contact, use with good ventilation
Potential Health Effects: Overexposure can lead to mild irritation in eyes, skin, and respiratory system
Environmental Effects: Low aquatic toxicity, low environmental persistence, steady biodegradation
Label Elements: No symbol requirement, plain labeling in accordance with safe chemical regulations
Other Hazards: Not flammable at room temperature, but excess heat increases risk of hazardous decomposition

Composition / Information on Ingredients

Chemical Name: Propylene Glycol BIO
Concentration: 99-100% by weight
Impurities: Trace water, potential contaminants at less than 0.1% total weight
CAS Number: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09 g/mol
Non-Hazardous Components: No ingredients classified as hazardous or carcinogenic
Ingredient Transparency: Meets requirements for food grade and pharmaceutical industries with stringent quality controls

First Aid Measures

Inhalation: Move exposed individual to fresh air, monitor for respiratory distress, administer oxygen if necessary, seek medical advice for prolonged symptoms
Skin Contact: Rinse skin with soap and water, remove contaminated clothing, persistent irritation requires consultation with a healthcare provider
Eye Contact: Flush with plenty of running water for at least 15 minutes, keep eyelids open and apart, remove contact lenses, medical attention for continued discomfort
Ingestion: Rinse mouth thoroughly, drink water to dilute, never induce vomiting, medical evaluation suggested for large accidental ingestions
Most Important Symptoms: Minor burning, itching, or redness in contact areas, gastrointestinal upset after swallowing large quantities
Notes to Physician: Treat symptomatically based on patient’s condition, supportive care as needed, no specific antidote

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical powder, CO2 extinguisher, foam
Unsuitable Media: Strong jets that may spread the burning liquid
Special Hazards: Combustion produces carbon monoxide, carbon dioxide, and other irritant fumes
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus required in confined areas
Fire and Explosion Hazards: Above flash point, vapor-air mixtures may ignite
Thermal Decomposition: Releases flammable and toxic gases under intense heat
Evacuation Recommendations: Move bystanders away from fire area, ensure good ventilation post-incident

Accidental Release Measures

Personal Precautions: Use personal protective equipment, avoid breathing vapors, collect with non-sparking tools
Environmental Precautions: Prevent entry to drains, soil, and natural waterways, contain spills with barriers
Cleanup Methods: Absorb with sand, earth, or inert absorbents, transfer to approved waste containers, flush residue with water while ensuring safe disposal
Emergency Procedures: Notify supervisory personnel and response teams, ventilate affected area
Disposal of Cleanup Materials: Treat as chemical waste, dispose at licensed facility, avoid disposal to surface water or sewer systems

Handling and Storage

Handling: Use with sufficient ventilation, avoid inhalation and prolonged skin exposure, practice standard hygiene after handling
Storage Requirements: Store in tightly sealed containers, keep away from heat, ignition sources, direct sunlight, and strong oxidizers
Temperature Control: Maintain ambient conditions, prevent freezing or overheating
Incompatible Materials: Strong acids, bases, oxidizing agents
Conditions to Avoid: Open flames, not to be stored with food or animal feed products
Storage Specification: Use corrosion-resistant tanks, secondary containment for spill protection

Exposure Controls and Personal Protection

Engineering Controls: Ensure local ventilation or exhaust at points of vapors or mist generation, install safety showers and eyewash stations
Occupational Exposure Limits: ACGIH TLV: 10 mg/m³ (aerosol, inhalable), OSHA PEL has not been established
Personal Protective Equipment: Eye protection with chemical splash goggles, gloves of nitrile or PVC, protective work clothing, respiratory protection for insufficient ventilation
Hygiene Measures: No eating, drinking, or smoking during use, thorough handwash after handling, remove contaminated clothing
Monitoring Procedures: Airborne levels should be monitored in areas prone to high vapor concentration

Physical and Chemical Properties

Appearance: Colorless, clear viscous liquid
Odor: Faintly sweet, almost odorless
Odor Threshold: Not noticeable at low concentrations
pH: Nearly neutral (6.0 – 7.5, 100g/l, 20°C)
Melting Point/Freezing Point: -59°C
Boiling Point: 188.2°C
Flash Point: 104°C (closed cup)
Evaporation Rate: Low
Flammability: Not readily flammable in normal conditions
Upper/Lower Flammability Limits: 2.6% – 12.6% volume in air
Vapor Pressure: 0.03 mmHg at 20°C
Vapor Density: 2.6 (Air=1)
Relative Density: 1.036 g/cm³ at 20°C
Solubility: Fully water-miscible
Partition Coefficient (n-octanol/water): -0.9
Autoignition Temperature: 421°C
Decomposition Temperature: Above 200°C
Viscosity: 58 mPa.s at 20°C

Stability and Reactivity

Chemical Stability: Stable under normal storage and operating conditions
Reactivity: Negligible in neutral settings, but reacts with strong oxidants
Compatible Materials: Most industrial materials except reactive chemicals
Hazardous Reactions: Potential hazard exists mixing with concentrated oxidizers or acids
Hazardous Decomposition Products: Carbon oxides, under fire or extended heating
Polymerization: Does not self-polymerize
Other Conditions to Avoid: Extreme heating, contamination with acidic or caustic substances, prolonged ultraviolet exposure without containment

Toxicological Information

Acute Toxicity: LD50 Oral (rat): 20,000–34,000 mg/kg, very low systemic toxicity
Skin Corrosion/Irritation: Mild, generally well-tolerated, repetitive exposure may dry skin
Serious Eye Damage/Irritation: Mild transient irritation
Respiratory or Skin Sensitization: Non-sensitizer
Germ Cell Mutagenicity: Not classified as mutagenic
Carcinogenicity: No data linking propylene glycol to cancer, not listed by IARC, NTP, or OSHA
Reproductive Toxicity: No evidence of reproductive health effects
Specific Target Organ Toxicity: No observed effects at industrial exposure levels
Chronic Effects: Not expected at low exposure, large quantities may stress liver and kidneys

Ecological Information

Ecotoxicity: Low aquatic toxicity, LC50 (Fish, 96hr): 40,000 mg/L, low toxicity to invertebrates and algae
Persistence and Degradability: Rapid biodegradation, breaks down naturally in water and soil
Bioaccumulative Potential: Low, does not persist in food chain
Mobility in Soil: High mobility, dilutes rapidly in presence of water
Other Adverse Effects: Extensive testing shows little impact on aquatic or terrestrial organisms at normal environmental concentrations

Disposal Considerations

Waste Treatment Methods: Chemical waste regulations govern disposal, treat as non-hazardous unless contaminated
Disposal Instructions: Disposal should follow local, regional, and national regulations
Preferred Disposal: Incineration in approved facility or other safe environmentally sound practices
Container Handling: Rinse thoroughly before recycling or discarding, labels removed before disposal
Recommendation: Seek guidance from licensed waste disposal contractor for bulk waste

Transport Information

UN Number: Not regulated for road, air, or sea transport
UN Shipping Name: Propylene Glycol BIO
Transport Hazard Classes: Not classified as dangerous goods
Packing Group: Not applicable
Environmental Hazards: None
Special Precautions: Secure containers to prevent leaks, protect from puncture during shipment
Transport Labels: None required under current standards

Regulatory Information

Inventory Listings: Propylene Glycol appears on TSCA, EINECS, DSL, and other national chemical inventories
OSHA Hazard Communication: Not hazardous according to US OSHA criteria
SARA Title III: No reportable components
California Proposition 65: Not listed
EU Regulations: Meets REACH requirements, not considered harmful or dangerous
WHMIS Classification: Not controlled
Other Country-Specific Regulations: Complies with labeling, safety, and environmental standards in major global markets